Sanford Health, a cornerstone of medical innovation in South Dakota, is poised to set a new milestone with the opening of a state-of-the-art orthopedic hospital tower in Sioux Falls. Located on the campus of Sanford University of South Dakota Medical Center, this nine-story marvel is scheduled to welcome its first patients in early 2026, marking a significant leap forward in the region’s healthcare landscape.
This cutting-edge facility will dramatically enhance surgical precision and patient care with its expanded surgery, imaging, and recovery spaces. The tower will house 12 advanced operating rooms designed to accommodate a range of orthopedic procedures, increasing the capacity for more specialized care within the community.
Sanford Health’s decision to expand in Sioux Falls underlines the city’s growing importance as a medical hub in the Midwest. By investing in this development, Sanford Health reinforces its commitment to providing world-class healthcare services to the residents of South Dakota and beyond.
Further enhancing the patient experience, the top two floors of the tower will feature the luxurious Highpoint Hotel, a boutique hotel specifically designed for patients and their families. This innovative concept offers convenience and comfort, ensuring that those undergoing treatment and their loved ones can stay close by, minimizing stress and facilitating recovery.

Sanford Health
Sioux Falls, widely recognized for its vibrant community and beautiful landscapes, provides an ideal setting for this expansive medical facility. As the largest city in South Dakota, Sioux Falls boasts a unique blend of small-town charm and metropolitan amenities, making it an attractive location for individuals seeking quality healthcare.
In recent years, South Dakota has emerged as a focal point for healthcare innovation, with institutions like Sanford Health leading the charge. The development of this new orthopedic tower aligns with South Dakota’s broader efforts to enhance its healthcare infrastructure and attract top medical talent to the state.
As Sanford Health charts a new course for orthopedic care in the region, the expected impact on the local economy cannot be overstated. The project will create numerous job opportunities for healthcare professionals, support staff, and construction workers, contributing to the economic vitality of Sioux Falls and its surrounding areas.
The remarkable transformation of Sanford University of South Dakota Medical Center’s campus with the addition of this new tower is a testament to Sanford Health’s forward-thinking strategy. It reflects a commitment to investing in the future of healthcare and meeting the evolving needs of patients with cutting-edge technology and compassionate care.

Sioux Falls
The Highpoint Hotel within the tower is a novel approach in healthcare hospitality. By providing a home away from home for families, Sanford Health aims to streamline the healthcare experience, ensuring that every aspect of patient care is attended to with attention to detail and a focus on well-being.
Looking ahead, the community eagerly anticipates the completion of the orthopedic hospital tower, a symbol of growth and the enduring spirit of innovation in Sioux Falls. As this landmark project moves forward, it stands as a beacon of hope and progress, highlighting the crucial role of South Dakota in shaping the future of healthcare.
With its grand opening just around the corner, Sanford Health’s newest venture is set to redefine healthcare standards not only for South Dakota but for the wider Midwest region. This monumental development is a clear indicator of a bright future for medical excellence in Sioux Falls.